ea0099ep390 | Adrenal and Cardiovascular Endocrinology | ECE2024
Peixe Carolina
, Vicente Rocha Jose
, De Grine Severino Mariana
, Lopes Marta
, Raquel Gomes Ana
, Ines Alexandre Maria
, Paula Barbosa Ana
Introduction: POEMS syndrome is a rare multisystem disorder characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma-proliferative disorder and skin changes. Different endocrinopathies are found in 58-80% of patients, however, its pathophysiology remains unknown. Hypogonadism (primary and secondary) is the most common endocrinopathy (79% of patients), with other abnormalities including hyperprolactinemia (56%), primary hypothyroidism (54%), abnormal glu...